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sellModerate cluster of 2

Opaleye Management Inc. sold $878k of CDXS

owner at CODEXIS, INC.. 514,341 shares at an average of $1.71, traded Nov 26, 2025, filed Dec 1, 2025.

Warning score
43
Value
$878k
514,341 shares
Holdings after
179,989
-5% from before
From 52-week low
+13%
low $1.54, close $1.74
From 52-week high
-70%
high $5.81, as of Nov 26, 2025

Score components

  • Role
    10% owner
    +12
  • Trade size
    $878k at market
    +23
  • Share of holdings sold
    Sold 4.9% of holdings
    0
  • Cluster
    2 insiders selling within 14 days
    +8

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

This signal so far: 1m -1.2%, 3m -38.2%, 6m +61.8%.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

CDXSOct 9, 2026 · close 1.41
Since filing Dec 1, 2025: -14.5%SPY +15.6% · excess -30.2%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001493152-25-025624, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Nov 26, 2025SOpen-market sale
Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P.
+148,318$1.74$258k10,305,000Dec 1, 2025
Nov 26, 2025SOpen-market sale
Common Stock, par value $0.001 per shareindirect: By Managed Account
-5,000$1.74$8,707191,012Dec 1, 2025
Nov 28, 2025SOpen-market sale
Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P.
-105,000$1.75$184k10,200,000Dec 1, 2025
Nov 28, 2025SOpen-market sale
Common Stock, par value $0.001 per shareindirect: By Managed Account
-2,490$1.75$4,358188,522Dec 1, 2025
Dec 1, 2025SOpen-market sale
Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P.
-245,000$1.67$409k9,955,000Dec 1, 2025
Dec 1, 2025SOpen-market sale
Common Stock, par value $0.001 per shareindirect: By Managed Account
-8,533$1.67$14k179,989Dec 1, 2025

Related signals

Other insiders at CODEXIS, INC. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
15Weak
CDXSsell
CODEXIS, INC.
Raymond De Vre
director
$6,174
2,605 shares
-3%
15Weak
CDXSsell
CODEXIS, INC.
Stefan Lutz
Chief Scientific Officer
$6,641
5,862 shares
-4%
40Moderate
CDXSsell 3
CODEXIS, INC.
Alison Moore
President and CEO
$5,001
3,826 shares
-2%
30Weak
CDXSsell 3
CODEXIS, INC.
Georgia Erbez
See Remarks
$5,001
3,826 shares
-5%
30Weak
CDXSsell 3
CODEXIS, INC.
Stefan Lutz
Chief Scientific Officer
$3,257
2,492 shares
-2%
15Weak
CDXSsell
CODEXIS, INC.
Stefan Lutz
CSO
$7,950
4,685 shares
-3%
52Moderate
CDXSsell 3
CODEXIS, INC.
Opaleye Management Inc.
owner
$1.9M
1,063,211 shares
-8%
43Moderate
CDXSsell 2
CODEXIS, INC.
Opaleye Management Inc.
owner
$878k
514,341 shares
-5%
30Weak
CDXSsell 3
CODEXIS, INC.
Dennis P Wolf
director
$14k
8,952 shares
-6%
52Moderate
CDXSsell 3
CODEXIS, INC.
Opaleye Management Inc.
owner
$2.1M
1,082,459 shares
-9%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Opaleye Management Inc. sold $878k of CDXS | InsiderTell