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sellModerate cluster of 3

Opaleye Management Inc. sold $2.1M of CDXS

owner at CODEXIS, INC.. 1,082,459 shares at an average of $1.94, traded Nov 12, 2025, filed Nov 14, 2025.

Warning score
52
Value
$2.1M
1,082,459 shares
Holdings after
10,453,318
-9% from before
From 52-week low
+14%
low $1.69, close $1.93
From 52-week high
-67%
high $5.81, as of Nov 12, 2025

Score components

  • Role
    10% owner
    +12
  • Trade size
    $2.1M at market
    +25
  • Share of holdings sold
    Sold 9.4% of holdings
    0
  • Cluster
    3 insiders selling within 14 days
    +15

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

This signal so far: 1m +1.2%, 3m -27.3%, 6m +49.1%.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

CDXSOct 13, 2026 · close 1.32
Since filing Nov 14, 2025: -20.0%SPY +17.0% · excess -37.0%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001493152-25-023486, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Nov 12, 2025SOpen-market sale
Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P.
+890,000$1.94$1.7M10,618,318Nov 14, 2025
Nov 12, 2025SOpen-market sale
Common Stock, par value $0.001 per shareindirect: By Managed Account
-27,459$1.94$53k196,012Nov 14, 2025
Nov 12, 2025SOpen-market sale
Common Stock, par value $0.001 per shareindirect: By Opaleye, L.P.
-165,000$1.96$324k10,453,318Nov 14, 2025

Related signals

Other insiders at CODEXIS, INC. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
15Weak
CDXSsell
CODEXIS, INC.
Raymond De Vre
director
$6,174
2,605 shares
-3%
15Weak
CDXSsell
CODEXIS, INC.
Stefan Lutz
Chief Scientific Officer
$6,641
5,862 shares
-4%
40Moderate
CDXSsell 3
CODEXIS, INC.
Alison Moore
President and CEO
$5,001
3,826 shares
-2%
30Weak
CDXSsell 3
CODEXIS, INC.
Georgia Erbez
See Remarks
$5,001
3,826 shares
-5%
30Weak
CDXSsell 3
CODEXIS, INC.
Stefan Lutz
Chief Scientific Officer
$3,257
2,492 shares
-2%
15Weak
CDXSsell
CODEXIS, INC.
Stefan Lutz
CSO
$7,950
4,685 shares
-3%
52Moderate
CDXSsell 3
CODEXIS, INC.
Opaleye Management Inc.
owner
$1.9M
1,063,211 shares
-8%
43Moderate
CDXSsell 2
CODEXIS, INC.
Opaleye Management Inc.
owner
$878k
514,341 shares
-5%
43Moderate
CDXSsell 2
CODEXIS, INC.
Opaleye Management Inc.
owner
$878k
514,341 shares
-5%
30Weak
CDXSsell 3
CODEXIS, INC.
Dennis P Wolf
director
$14k
8,952 shares
-6%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Opaleye Management Inc. sold $2.1M of CDXS | InsiderTell