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sellWeak10b5-1 plan

James C Hamilton sold $700k of ARWR

Chief Medical Officer at ARROWHEAD PHARMACEUTICALS, INC.. 20,000 shares at an average of $35.00, traded Oct 1, 2025, filed Oct 3, 2025.

Warning score
16
Value
$700k
20,000 shares
Holdings after
212,122
-9% from before
From 52-week low
+250%
low $9.99, close $35.01
From 52-week high
0%
high $35.01, as of Oct 1, 2025

Score components

  • Role
    Officer
    +15
  • Trade size
    $700k at market
    +21
  • Share of holdings sold
    Sold 8.6% of holdings
    0
  • Cluster
    No other insider selling within 14 days
    0
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

ARWROct 9, 2026 · close 62.75
Since filing Oct 3, 2025: +73.7%SPY +17.6% · excess +56.1%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001830755-25-000011, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Oct 1, 2025SOpen-market sale
Common Stock10b5-1
-20,000$35.00$700k212,122Oct 3, 2025

Related signals

Other insiders at ARROWHEAD PHARMACEUTICALS, INC. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
15Weak
ARWRsell10b5-1
ARROWHEAD PHARMACEUTICALS, INC.
James C Hamilton
Chief Medical Officer
$642k
10,000 shares
-4%
43Moderate
ARWRsell 710b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Christopher Richard Anzalone
Chief Executive Officer
$872k
13,187 shares
-0%
40Moderate
ARWRsell 410b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Patrick O'Brien
COO
$3.1M
49,493 shares
-9%
40Moderate
ARWRsell 410b5-1
ARROWHEAD PHARMACEUTICALS, INC.
James C Hamilton
Chief Medical Officer
$2.5M
40,164 shares
-19%
30Weak
ARWRsell 710b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Christopher Richard Anzalone
Chief Executive Officer
$3.6M
51,726 shares
-1%
28Weak
ARWRsell 710b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Mauro Ferrari
director
$527k
7,530 shares
-10%
35Weak
ARWRsell 610b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Adeoye Y Olukotun
director
$677k
10,000 shares
-23%
45Moderate
ARWRsell 610b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Christopher Richard Anzalone
Chief Executive Officer
$1.8M
26,031 shares
-1%
34Weak
ARWRsell 610b5-1
ARROWHEAD PHARMACEUTICALS, INC.
William D. Waddill
director
$566k
8,367 shares
-13%
36Weak
ARWRsell 610b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Victoria Vakiener
director
$679k
10,040 shares
-22%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.