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sellNotable cluster of 6

Christopher Richard Anzalone sold $12M of ARWR

Chief Executive Officer at ARROWHEAD PHARMACEUTICALS, INC.. 184,298 shares at an average of $67.00, traded Dec 15, 2025, filed Dec 16, 2025.

Warning score
65
Value
$12M
184,298 shares
Holdings after
3,916,957
-4% from before
From 52-week low
+585%
low $9.99, close $68.45
From 52-week high
-3%
high $70.82, as of Dec 15, 2025

Score components

  • Role
    CEO
    +25
  • Trade size
    $12.3M at market
    +25
  • Share of holdings sold
    Sold 4.5% of holdings
    0
  • Cluster
    6 insiders selling within 14 days
    +15

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

ARWROct 9, 2026 · close 62.75
Since filing Dec 16, 2025: -3.0%SPY +15.9% · excess -18.9%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001423029-25-000003, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Dec 12, 2025AGrant or award
Common Stock
+180,000$0.00$04,101,255Dec 16, 2025
Dec 15, 2025SOpen-market sale
Common Stock
-100,532$68.67$6.9M4,000,723Dec 16, 2025
Dec 15, 2025SOpen-market sale
Common Stock
-21,321$69.28$1.5M3,979,402Dec 16, 2025
Dec 15, 2025SOpen-market sale
Common Stock
-8,147$69.96$570k3,971,255Dec 16, 2025
Dec 16, 2025SOpen-market sale
Common Stock
-8,416$60.51$509k3,962,839Dec 16, 2025
Dec 16, 2025SOpen-market sale
Common Stock
-10,963$61.25$671k3,951,876Dec 16, 2025
Dec 16, 2025SOpen-market sale
Common Stock
-14,095$62.12$876k3,937,781Dec 16, 2025
Dec 16, 2025SOpen-market sale
Common Stock
-8,476$62.94$533k3,929,305Dec 16, 2025
Dec 16, 2025SOpen-market sale
Common Stock
-6,661$64.29$428k3,922,644Dec 16, 2025
Dec 16, 2025SOpen-market sale
Common Stock
-1,000$64.96$65k3,921,644Dec 16, 2025
Dec 16, 2025SOpen-market sale
Common Stock
-1,300$65.77$86k3,920,344Dec 16, 2025
Dec 16, 2025SOpen-market sale
Common Stock
-166$66.77$11k3,920,178Dec 16, 2025
Dec 16, 2025SOpen-market sale
Common Stock
-3,221$67.87$219k3,916,957Dec 16, 2025

Related signals

Other insiders at ARROWHEAD PHARMACEUTICALS, INC. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
15Weak
ARWRsell10b5-1
ARROWHEAD PHARMACEUTICALS, INC.
James C Hamilton
Chief Medical Officer
$642k
10,000 shares
-4%
43Moderate
ARWRsell 710b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Christopher Richard Anzalone
Chief Executive Officer
$872k
13,187 shares
-0%
40Moderate
ARWRsell 410b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Patrick O'Brien
COO
$3.1M
49,493 shares
-9%
40Moderate
ARWRsell 410b5-1
ARROWHEAD PHARMACEUTICALS, INC.
James C Hamilton
Chief Medical Officer
$2.5M
40,164 shares
-19%
30Weak
ARWRsell 710b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Christopher Richard Anzalone
Chief Executive Officer
$3.6M
51,726 shares
-1%
28Weak
ARWRsell 710b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Mauro Ferrari
director
$527k
7,530 shares
-10%
35Weak
ARWRsell 610b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Adeoye Y Olukotun
director
$677k
10,000 shares
-23%
45Moderate
ARWRsell 610b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Christopher Richard Anzalone
Chief Executive Officer
$1.8M
26,031 shares
-1%
34Weak
ARWRsell 610b5-1
ARROWHEAD PHARMACEUTICALS, INC.
William D. Waddill
director
$566k
8,367 shares
-13%
36Weak
ARWRsell 610b5-1
ARROWHEAD PHARMACEUTICALS, INC.
Victoria Vakiener
director
$679k
10,040 shares
-22%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Christopher Richard Anzalone sold $12M of ARWR | InsiderTell