Alex Nemiroff sold $4.9M of PRAX
General Counsel and Secretary at Praxis Precision Medicines, Inc.. 25,130 shares at an average of $193.09, traded Nov 20, 2025, filed Nov 21, 2025.
Score components
- +15RoleOfficer
- +25Trade size$4.9M at market
- +20Share of holdings soldSold 55% of holdings
- +8Cluster2 insiders selling within 14 days
- -15Exercise and sellShares came from an option exercise in the same filing
What happened after comparable sells
Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.
This signal so far: 1m +60.7%, 3m +97.5%, 6m +102.3%.
Price around the trade, and since
From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.
Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™
Rows in this filing
Every transaction in Form 4 0001104659-25-115099, as filed. Open on EDGAR
| Date | Transaction | Shares | Price | Value | Holdings after | Filed |
|---|---|---|---|---|---|---|
| Nov 20, 2025 | MOption exercise Common Stock | +1,714 | $83.85 | $144k | 22,546 | Nov 21, 2025 |
| Nov 20, 2025 | MOption exercise Common Stock | +6,230 | $133.65 | $833k | 28,776 | Nov 21, 2025 |
| Nov 20, 2025 | MOption exercise Common Stock | +2,434 | $44.40 | $108k | 31,210 | Nov 21, 2025 |
| Nov 20, 2025 | MOption exercise Common Stock | +5,652 | $44.40 | $251k | 36,862 | Nov 21, 2025 |
| Nov 20, 2025 | MOption exercise Common Stock | +9,100 | $56.94 | $518k | 45,962 | Nov 21, 2025 |
| Nov 20, 2025 | SOpen-market sale Common Stock | -1,714 | $190.86 | $327k | 44,248 | Nov 21, 2025 |
| Nov 20, 2025 | SOpen-market sale Common Stock | -13,339 | $192.53 | $2.6M | 30,909 | Nov 21, 2025 |
| Nov 20, 2025 | SOpen-market sale Common Stock | -977 | $193.23 | $189k | 29,932 | Nov 21, 2025 |
| Nov 20, 2025 | SOpen-market sale Common Stock | -9,100 | $194.30 | $1.8M | 20,832 | Nov 21, 2025 |
| Nov 20, 2025 | MOption exercise Stock Option (Right to Buy)derivative | -1,714 | $0.00 | $0 | 0 | Nov 21, 2025 |
| Nov 20, 2025 | MOption exercise Stock Option (Right to Buy)derivative | -6,230 | $0.00 | $0 | 0 | Nov 21, 2025 |
| Nov 20, 2025 | MOption exercise Stock Option (Right to Buy)derivative | -2,434 | $0.00 | $0 | 0 | Nov 21, 2025 |
| Nov 20, 2025 | MOption exercise Stock Option (Right to Buy)derivative | -5,652 | $0.00 | $0 | 2,347 | Nov 21, 2025 |
| Nov 20, 2025 | MOption exercise Stock Option (Right to Buy)derivative | -9,100 | $0.00 | $0 | 19,717 | Nov 21, 2025 |
Related signals
Other insiders at Praxis Precision Medicines, Inc. and this insider’s other filings.
| Score | Company | Insider | Value | Holdings | Filed |
|---|---|---|---|---|---|
| 25Weak | Praxis Precision Medicines, Inc. | Jill DeSimone director | $3.6M 11,600 shares | -83% | |
| 53Moderate | Praxis Precision Medicines, Inc. | Lauren Mastrocola Principal Accounting Officer | $2.6M 13,600 shares | -57% | |
| 42Moderate | PRAXsell Praxis Precision Medicines, Inc. | Adage Capital Management, L.P. owner | $33M 313,910 shares | -13% | |
| 34Weak | Praxis Precision Medicines, Inc. | Lauren Mastrocola Principal Accounting Officer | $424k 5,188 shares | -48% | |
| 38Weak | Praxis Precision Medicines, Inc. | Alex Nemiroff General Counsel and Secretary | $661k 8,239 shares | -44% | |
| 39Weak | PRAXbuy Praxis Precision Medicines, Inc. | Marcio Souza Chief Executive Officer | $11k 10,000 shares | +29% | |
| 61Notable | Praxis Precision Medicines, Inc. | Timothy Edwin Kelly Chief Financial Officer | $6,998 8,000 shares | +21% | |
| 61Notable | Praxis Precision Medicines, Inc. | Timothy Edwin Kelly Chief Financial Officer | $6,998 8,000 shares | +21% | |
| 64Notable | Praxis Precision Medicines, Inc. | Dean J Mitchell director | $42k 50,000 shares | +200% | |
| 71Notable | Praxis Precision Medicines, Inc. | Marcio Souza Chief Executive Officer | $60k 70,002 shares | +37% |
Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.