Skip to content
sellWeak10b5-1 plan

Jill DeSimone sold $3.6M of PRAX

director at Praxis Precision Medicines, Inc.. 11,600 shares at an average of $311.32, traded Jun 24, 2026, filed Jun 26, 2026.

Warning score
25
Value
$3.6M
11,600 shares
Holdings after
2,337
-83% from before
From 52-week low
+719%
low $37.71, close $308.94
From 52-week high
-13%
high $357.13, as of Jun 24, 2026

Score components

  • Role
    Director
    +15
  • Trade size
    $3.6M at market
    +25
  • Share of holdings sold
    Sold 83% of holdings
    +20
  • Cluster
    No other insider selling within 14 days
    0
  • Exercise and sell
    Shares came from an option exercise in the same filing
    -15
  • 10b5-1 plan
    Pre-scheduled under a 10b5-1 plan
    -20

What happened after comparable sells

Same side and tier, against the S&P 500, at 1, 3 and 6 months. Shown to Pro users; the whole table is on the backtest page.

Price around the trade, and since

From a quarter before the trade to today. The arrow is the trade, the circle the day the filing reached EDGAR, which is the first day anyone outside could act; the dotted line is the S&P 500 rebased to that day's close.

PRAXOct 14, 2026 · close 239.02
Since filing Jun 26, 2026: -27.1%SPY +5.8% · excess -32.9%

Daily candles, adjusted for splits and dividends. Green arrows are insider buys, red are sells, sized by value; the dashed line is the close on the filing day, the dotted line SPY rebased to it.Charts by TradingView Lightweight Charts™

Rows in this filing

Every transaction in Form 4 0001930479-26-000003, as filed. Open on EDGAR

DateTransactionSharesPriceValueHoldings afterFiled
Jun 24, 2026MOption exercise
Common Stock10b5-1
+8,566$44.25$379k10,903Jun 26, 2026
Jun 24, 2026MOption exercise
Common Stock10b5-1
+3,034$147.30$447k13,937Jun 26, 2026
Jun 24, 2026SOpen-market sale
Common Stock10b5-1
-10$301.44$3,01413,927Jun 26, 2026
Jun 24, 2026SOpen-market sale
Common Stock10b5-1
-120$303.13$36k13,807Jun 26, 2026
Jun 24, 2026SOpen-market sale
Common Stock10b5-1
-320$305.31$98k13,487Jun 26, 2026
Jun 24, 2026SOpen-market sale
Common Stock10b5-1
-683$306.77$210k12,804Jun 26, 2026
Jun 24, 2026SOpen-market sale
Common Stock10b5-1
-1,240$308.24$382k11,564Jun 26, 2026
Jun 24, 2026SOpen-market sale
Common Stock10b5-1
-999$309.38$309k10,565Jun 26, 2026
Jun 24, 2026SOpen-market sale
Common Stock10b5-1
-1,750$310.89$544k8,815Jun 26, 2026
Jun 24, 2026SOpen-market sale
Common Stock10b5-1
-2,854$311.91$890k5,961Jun 26, 2026
Jun 24, 2026SOpen-market sale
Common Stock10b5-1
-1,004$312.83$314k4,957Jun 26, 2026
Jun 24, 2026SOpen-market sale
Common Stock10b5-1
-504$313.66$158k4,453Jun 26, 2026
Jun 24, 2026SOpen-market sale
Common Stock10b5-1
-1,279$314.90$403k3,174Jun 26, 2026
Jun 24, 2026SOpen-market sale
Common Stock10b5-1
-837$315.71$264k2,337Jun 26, 2026
Jun 24, 2026MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-8,566$0.00$00Jun 26, 2026
Jun 24, 2026MOption exercise
Stock Option (Right to Buy)derivative10b5-1
-3,034$0.00$00Jun 26, 2026

Related signals

Other insiders at Praxis Precision Medicines, Inc. and this insider’s other filings.

ScoreCompanyInsiderValueHoldingsFiled
53Moderate
PRAXsell 2
Praxis Precision Medicines, Inc.
Lauren Mastrocola
Principal Accounting Officer
$2.6M
13,600 shares
-57%
53Moderate
PRAXsell 2
Praxis Precision Medicines, Inc.
Alex Nemiroff
General Counsel and Secretary
$4.9M
25,130 shares
-55%
42Moderate
PRAXsell
Praxis Precision Medicines, Inc.
Adage Capital Management, L.P.
owner
$33M
313,910 shares
-13%
34Weak
PRAXsell 2
Praxis Precision Medicines, Inc.
Lauren Mastrocola
Principal Accounting Officer
$424k
5,188 shares
-48%
38Weak
PRAXsell 2
Praxis Precision Medicines, Inc.
Alex Nemiroff
General Counsel and Secretary
$661k
8,239 shares
-44%
39Weak
PRAXbuy
Praxis Precision Medicines, Inc.
Marcio Souza
Chief Executive Officer
$11k
10,000 shares
+29%
61Notable
PRAXbuy 3
Praxis Precision Medicines, Inc.
Timothy Edwin Kelly
Chief Financial Officer
$6,998
8,000 shares
+21%
61Notable
PRAXbuy 3
Praxis Precision Medicines, Inc.
Timothy Edwin Kelly
Chief Financial Officer
$6,998
8,000 shares
+21%
64Notable
PRAXbuy 3
Praxis Precision Medicines, Inc.
Dean J Mitchell
director
$42k
50,000 shares
+200%
71Notable
PRAXbuy 3
Praxis Precision Medicines, Inc.
Marcio Souza
Chief Executive Officer
$60k
70,002 shares
+37%

Not investment advice. Scores and forward returns are decision support built from public SEC filings and past prices; they describe what happened after comparable filings, not what will happen after this one. Do your own research and size your risk.

Jill DeSimone sold $3.6M of PRAX | InsiderTell